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Article

Control of translation initiation involves a factor-induced rearrangement of helix 44 of 16S ribosomal RNA.

Molecular microbiology - 1 Mar 2009

Qin Daoming, Fredrick Kurt

Abstract excerpt

Initiation of translation involves recognition of the start codon by the initiator tRNA in the 30S subunit. To investigate the role of ribosomal RNA (rRNA) in this process, we isolated a number of 16S rRNA mutations that increase translation from the non-canonical start codon AUC. These mutations cluster to distinct regions that overlap remarkably well with previously identified class III protection sites and...

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Share to Escherichia coli
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nucleic Acid Conformation

Share to Peptide Chain Initiation, Translational

Share to RNA, Bacterial

Share to RNA, Ribosomal, 16S

Share to RNA, Transfer, Met

Source

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Identifiers

PMID: 19154330
DOI: 10.1111/j.1365-2958.2009.06598.x
PMCID: PMC3647337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of 16S rRNA mutations that decrease the fidelity of translation initiation.Semantic proximity Read ↗

Role of helix 44 of 16S rRNA in the fidelity of translation initiation.Semantic proximity Read ↗

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