Article
New variants of B16 mouse melanoma: differentiation and metastatic properties.
Pigment cell research - 1 Jan 2000
Aubert C, Voulot C, Rouge F, Pirisi V, Galindo J R
Abstract excerpt
A system of tumor transplantation has been developed to select metastatic variants of B16 in mutants of the C57BL/6J black strain of mice. The effects of transplantation into nonagouti a/a and mutant recipients on the production of melanin and on the metastatic potential of tumors were investigated. Transplantation of the pigmented B16 melanoma from a nonagouti black a/a host to a yellow mutant Ay/a recipient...
Topics
- Animals
- Cell Line
- Cell Transformation, Neoplastic
- Genetic Variation
- Lung Neoplasms
- Melanoma, Experimental
- Mice
- Neoplasm Metastasis
- Tumor Cells, Cultured