Article
Metastatic variants of the B16 melanoma: metastasis is related to environmental conditions. Genetic and metabolic effects.
Melanoma research - 1 Aug 1994
Aubert C
Abstract excerpt
Using variant B16 metastatic melanomas, attempts were made to explore the effects of both genetic and metabolic environmental factors in vivo as well as in vitro, on specific steps in the metastatic process. Metastases of the progenitor tumour in black C57BL/6J mice arose from a stable, heritable, non-random, pre-existing subpopulation of metastatic cells. In vitro, the environment influenced both pigmentary and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
