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Article

Critical determinants of melanoma metastasis.

The journal of investigative dermatology. Symposium proceedings - 1 Apr 1996

Fidler I J

Abstract excerpt

The process of metastasis consists of a series of linked, sequential steps. Although some of the steps in this process contain stochastic elements, metastasis as a whole favors the survival and growth of a few subpopulations of cells that preexist within the parent neoplasm. Metastases can have a clonal origin, and different metastases can originate from the proliferation of single cells. The outcome of...

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PMID: 9627717

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