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Article

Dynamic heterogeneity: metastatic variants to liver are generated spontaneously in mouse embryonal carcinoma cells.

Clinical & experimental metastasis - 1 Jan 2000

Harris J F, Best M W

Abstract excerpt

Mouse embryonal carcinoma (EC) cells derived from F9 cells form predominantly liver tumors following the intravenous injection (i.e. experimental metastasis assay) of EC cells into syngeneic 129/J male mice. In this study, EC cells (OTF9) expressing stage-specific embryonic antigen-1 (SSEA-1) are compared with cells (SOTF9) lacking SSEA-1 antigen in the experimental liver metastasis assay. When parallel clones of...

Topics

Animals
Antigens, Neoplasm
Cell Line
Clone Cells
Glycolipids
Lewis X Antigen
Liver
Liver Neoplasms, Experimental
Male
Mice
Models, Biological
Neoplasm Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Organ Specificity

Phenotype

Transplantation, Isogeneic

Tumor Cells, Cultured

Tumor Stem Cell Assay

Source

Identifiers

PMID: 2900709
DOI: 10.1007/BF01784376

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2900709-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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