Metastatic variants of the B16 melanoma: metastasis is related to environmental conditions. Phenotypic changes in vitro and metastatic colonization potential in nude mice.

Article

Metastatic variants of the B16 melanoma: metastasis is related to environmental conditions. Phenotypic changes in vitro and metastatic colonization potential in nude mice.

Melanoma research - 1 Jun 1995

Aubert C

Abstract excerpt

Variants of B16 melanoma exhibit strikingly different metastatic potential in AY/a (YB16 tumours) and a/a C57BL/6J (MB16 tumours) syngeneic mice. This study focused on relative pigmentation and metastatic potential in eight subline cultures initiated from B16 control and YB16 and MB16 tumours. Du...

Topics

Animals
Cell Differentiation
Female
Lung Neoplasms
Male
Melanoma, Experimental
Mice
Mice, Inbred C57BL
Mice, Nude
Phenotype
Pigmentation
Tumor Cells, Cultured

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