Article
Use of NeoR B16F1 murine melanoma cells to assess clonality of experimental metastases in the immune-deficient chick embryo.
Clinical & experimental metastasis - 1 Jan 2000
Chambers A F, Wilson S
Abstract excerpt
Recent work on molecular and genetic aspects of metastasis has emphasized the need for assays in immune-deficient animal hosts. The commonly used assays in athymic nude mice may not always be appropriate, and assays in other hosts are required. We have developed a metastasis assay in the naturall...
Topics
- Animals
- Chick Embryo
- Genes, Bacterial
- Genetic Markers
- Immunologic Deficiency Syndromes
- Melanoma
- Mice
- Phenotype
- Tumor Cells, Cultured