Article
Differentiation and the tumorigenic and metastatic phenotype of murine melanoma cells.
International journal of cancer - 15 Jun 1990
Kameyama K, Vieira W D, Tsukamoto K, Law L W, Hearing V J
Abstract excerpt
Using B16 F10 murine melanoma cells and sublines generated from the JB/MS melanoma which exhibit various degrees of melanogenesis, the relationships among differentiation, tumorigenicity, and metastatic potential were examined. The effect of melanocyte-stimulating hormone (MSH), which specificall...
Topics
- Animals
- Cell Line
- Cell Transformation, Neoplastic
- Clone Cells
- Female
- Flow Cytometry
- Interferon-gamma
- Killer Cells, Natural
- Melanoma, Experimental
- Mice
- Mice, Inbred C57BL
- Neoplasm Metastasis
- Neoplasm Transplantation
- Phenotype
- Receptors, Pituitary Hormone
- Recombinant Proteins
- Specific Pathogen-Free Organisms
- Tumor Cells, Cultured