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Article

Genetic polymorphisms in the endotoxin receptor may influence platelet count as part of the acute phase response in critically ill children.

Intensive care medicine - 1 Jun 2010

Agbeko Rachel S, Holloway John W, Allen Meredith L, Ye Shu, Fidler Katy J, Pappachan John, Goldman Allan, Pontefract David, Deanfield John, Klein Nigel J, Peters Mark J

Abstract excerpt

PURPOSE: To determine if common polymorphisms in the endotoxin recognition complex influence the acute phase response as determined by the development of the systemic inflammatory response syndrome (SIRS) and platelet count on admission. METHODS: This was a prospective observational cohort study....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20237756
DOI: 10.1007/s00134-010-1857-x

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20237756-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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