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Article

Genetic variability in complement activation modulates the systemic inflammatory response syndrome in children.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies - 1 Sept 2010

Agbeko Rachel S, Fidler Katy J, Allen Meredith L, Wilson Peter, Klein Nigel J, Peters Mark J

Abstract excerpt

OBJECTIVE: To determine the impact of genetic variability in complement activation on early development of the systemic inflammatory response syndrome (SIRS) in general pediatric critical care. DESIGN: Prospective, observational, cohort study. SETTING: A tertiary pediatric intensive care unit in the United Kingdom. PATIENTS: Children with at least one organ failure expected to stay in the intensive care unit >12...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20351616
DOI: 10.1097/PCC.0b013e3181d900ba

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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