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Article

Influence of pentraxin 3 (PTX3) genetic variants on myocardial infarction risk and PTX3 plasma levels.

PloS one - 1 Jan 2012

Barbati Elisa, Specchia Claudia, Villella Massimo, Rossi Marco Luciano, Barlera Simona, Bottazzi Barbara, Crociati Luisa, d'Arienzo Carmela, Fanelli Raffaele, Garlanda Cecilia, Gori Francesca, Mango Ruggiero, Mantovani Alberto, Merla Giuseppe, Nicolis Enrico B, Pietri Silvia, Presbitero Patrizia, Sudo Yukio, Villella Alessandro, Franzosi Maria Grazia

Abstract excerpt

PTX3 is a long pentraxin of the innate immune system produced by different cell types (mononuclear phagocytes, dendritic cells, fibroblasts and endothelial cells) at the inflammatory site. It appears to have a cardiovascular protective function by acting on the immune-inflammatory balance in the cardiovascular system. PTX3 plasma concentration is an independent predictor of mortality in patients with acute...

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Identifiers

PMID: 23285251
DOI: 10.1371/journal.pone.0053030
PMCID: PMC3532160

Genes

PTX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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