Article
The role of TLR4 in endotoxin responsiveness in humans.
Journal of endotoxin research - 1 Jan 2001
Schwartz D A
Abstract excerpt
Despite the tremendous inter-individual variability in the response to inhaled toxins, we simply do not understand why certain people develop disease when challenged with environmental agents and others remain healthy. To address this concern, we investigated whether the Toll-4 (TLR4) gene, that has been shown to affect lipopolysaccharide (LPS) responsiveness in mice, underlies the variability in airway...
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