Performance of common genetic variants in breast-cancer risk models.

doi:10.1056/NEJMoa0907727

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Article

Performance of common genetic variants in breast-cancer risk models.

The New England journal of medicine - 18 Mar 2010

Wacholder Sholom, Hartge Patricia, Prentice Ross, Garcia-Closas Montserrat, Feigelson Heather Spencer, Diver W Ryan, Thun Michael J, Cox David G, Hankinson Susan E, Kraft Peter, Rosner Bernard, Berg Christine D, Brinton Louise A, Lissowska Jolanta, Sherman Mark E, Chlebowski Rowan, Kooperberg Charles, Jackson Rebecca D, Buckman Dennis W, Hui Peter, Pfeiffer Ruth, Jacobs Kevin B, Thomas Gilles D, Hoover Robert N, Gail Mitchell H, Chanock Stephen J, Hunter David J

Abstract excerpt

BACKGROUND: Genomewide association studies have identified multiple genetic variants associated with breast cancer. The extent to which these variants add to existing risk-assessment models is unknown. METHODS: We used information on traditional risk factors and 10 common genetic variants associated with breast cancer in 5590 case subjects and 5998 control subjects, 50 to 79 years of age, from four U.S. cohort...

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Identifiers

PMID: 20237344
DOI: 10.1056/NEJMoa0907727
PMCID: PMC2921181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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