Article
Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry.
Breast cancer research : BCR - 8 Dec 2016
Wen Wanqing, Shu Xiao-Ou, Guo Xingyi, Cai Qiuyin, Long Jirong, Bolla Manjeet K, Michailidou Kyriaki, Dennis Joe, Wang Qin, Gao Yu-Tang, Zheng Ying, Dunning Alison M, García-Closas Montserrat, Brennan Paul, Chen Shou-Tung, Choi Ji-Yeob, Hartman Mikael, Ito Hidemi, Lophatananon Artitaya, Matsuo Keitaro, Miao Hui, Muir Kenneth, Sangrajrang Suleeporn, Shen Chen-Yang, Teo Soo H, Tseng Chiu-Chen, Wu Anna H, Yip Cheng Har, Simard Jacques, Pharoah Paul D P, Hall Per, Kang Daehee, Xiang Yongbing, Easton Douglas F, Zheng Wei
Abstract excerpt
BACKGROUND: Approximately 100 common breast cancer susceptibility alleles have been identified in genome-wide association studies (GWAS). The utility of these variants in breast cancer risk prediction models has not been evaluated adequately in women of Asian ancestry. METHODS: We evaluated 88 breast cancer risk variants that were identified previously by GWAS in 11,760 cases and 11,612 controls of Asian...
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