Article
Improved prediction of complex diseases by common genetic markers: state of the art and further perspectives.
Human genetics - 1 Mar 2016
Müller Bent, Wilcke Arndt, Boulesteix Anne-Laure, Brauer Jens, Passarge Eberhard, Boltze Johannes, Kirsten Holger
Abstract excerpt
Reliable risk assessment of frequent, but treatable diseases and disorders has considerable clinical and socio-economic relevance. However, as these conditions usually originate from a complex interplay between genetic and environmental factors, precise prediction remains a considerable challenge. The current progress in genotyping technology has resulted in a substantial increase of knowledge regarding the...
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