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Article

Genetic risk prediction in complex disease.

Human molecular genetics - 15 Oct 2011

Jostins Luke, Barrett Jeffrey C

Abstract excerpt

Attempting to classify patients into high or low risk for disease onset or outcomes is one of the cornerstones of epidemiology. For some (but by no means all) diseases, clinically usable risk prediction can be performed using classical risk factors such as body mass index, lipid levels, smoking status, family history and, under certain circumstances, genetics (e.g. BRCA1/2 in breast cancer). The advent of...

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PMID: 21873261
DOI: 10.1093/hmg/ddr378
PMCID: PMC3179379

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BRCA1

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