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Article

Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk.

Journal of the National Cancer Institute - 16 Jul 2008

Gail Mitchell H

Abstract excerpt

One purpose for seeking common alleles that are associated with disease is to use them to improve models for projecting individualized disease risk. Two genome-wide association studies and a study of candidate genes recently identified seven common single-nucleotide polymorphisms (SNPs) that were associated with breast cancer risk in independent samples. These seven SNPs were located in FGFR2, TNRC9 (now known as...

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Research Design
Area Under Curve
Biomarkers, Tumor
Logistic Models
Models, Statistical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Predictive Value of Tests

Risk Assessment

Sensitivity and Specificity

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Open in PubMed Open full text

Identifiers

PMID: 18612136
DOI: 10.1093/jnci/djn180
PMCID: PMC2528005

Genes

CASP8
FGFR2
LSP1
TOX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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