Article
Common Genetic Variation and Breast Cancer Risk-Past, Present, and Future.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2018
Lilyquist Jenna, Ruddy Kathryn J, Vachon Celine M, Couch Fergus J
Abstract excerpt
Breast cancer is the most common cancer among women in the United States, with up to 30% of those diagnosed displaying a family history of breast cancer. To date, 18% of the familial risk of breast cancer can be explained by SNPs. This review summarizes the discovery of risk-associated SNPs using candidate gene and genome-wide association studies (GWAS), including discovery and replication in large collaborative...
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