Article
Genetic and clinical predictors for breast cancer risk assessment and stratification among Chinese women.
Journal of the National Cancer Institute - 7 Jul 2010
Zheng Wei, Wen Wanqing, Gao Yu-Tang, Shyr Yu, Zheng Ying, Long Jirong, Li Guoliang, Li Chun, Gu Kai, Cai Qiuyin, Shu Xiao-Ou, Lu Wei
Abstract excerpt
BACKGROUND: Most of the genetic variants identified from genome-wide association studies of breast cancer have not been validated in Asian women. No risk assessment model that incorporates both genetic and clinical predictors is currently available to predict breast cancer risk in this population. METHODS: We analyzed 12 single-nucleotide polymorphisms (SNPs) identified in recent genome-wide association studies...
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