Article
Distribution Analysis of Deacetylase SIRT1 in Rodent and Human Nervous Systems
11 Mar 2010
Abstract excerpt
Sirtuins function with other biogenic molecules to promote adaptation to caloric restriction in a broad spectrum of eukaryotic species. Sirtuin pathways also converge in the mammalian brain where they appear to protect neurons from nutrient stress. However, few anatomical studies on sirtuins (e.g., SIRT1) are available, particularly those detailing the spatial distribution and subcellular localization pattern of...
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