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Article

MRC1-dependent scaling of the budding yeast DNA replication timing program.

Genome research - 1 Jun 2010

Koren Amnon, Soifer Ilya, Barkai Naama

Abstract excerpt

We describe the DNA replication timing programs of 14 yeast mutants with an extended S phase identified by a novel genome-wide screen. These mutants are associated with the DNA replication machinery, cell-cycle control, and dNTP synthesis and affect different parts of S phase. In 13 of the mutants, origin activation time scales with the duration of S phase. A limited number of origins become inactive in these...

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Source

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Identifiers

PMID: 20219942
DOI: 10.1101/gr.102764.109
PMCID: PMC2877575

Genes

MRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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