Article
Regulation of DNA-replication origins during cell-cycle progression.
Nature - 8 Oct 1998
Shirahige K, Hori Y, Shiraishi K, Yamashita M, Takahashi K, Obuse C, Tsurimoto T, Yoshikawa H
Abstract excerpt
We have shown previously that chromosome VI of Saccharomyces cerevisiae contains nine origins of DNA replication that differ in initiation frequency and replicate sequentially during the S phase of the cell cycle. Here we show that there are links between activation of these multiple origins and...
Topics
- Cell Cycle
- Cell Cycle Proteins
- Checkpoint Kinase 2
- DNA Replication
- DNA, Fungal
- DNA-Binding Proteins
- Methyl Methanesulfonate
- Mutagens
- Mutation
- Origin Recognition Complex
- Protein Kinases
- Protein Serine-Threonine Kinases
- Replication Origin
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins