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Article

The spatial and temporal organization of origin firing during the S-phase of fission yeast.

Genome research - 1 Mar 2015

Kaykov Atanas, Nurse Paul

Abstract excerpt

Eukaryotes duplicate their genomes using multiple replication origins, but the organization of origin firing along chromosomes and during S-phase is not well understood. Using fission yeast, we report the first genome-wide analysis of the spatial and temporal organization of replication origin firing, analyzed using single DNA molecules that can approach the full length of chromosomes. At S-phase onset, origins...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25650245
DOI: 10.1101/gr.180372.114
PMCID: PMC4352884

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