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Article

HIV drug resistance surveillance using pooled pyrosequencing.

PloS one - 17 Feb 2010

Ji Hezhao, Massé Nathalie, Tyler Shaun, Liang Ben, Li Yang, Merks Harriet, Graham Morag, Sandstrom Paul, Brooks James

Abstract excerpt

BACKGROUND: Surveillance for HIV transmitted drug resistance (TDR) is performed using HIV genotype results from individual specimens. Pyrosequencing, through its massive parallel sequencing ability, can analyze large numbers of specimens simultaneously. Instead of using pyrosequencing conventionally, to sequence a population of viruses within an individual, we interrogated a single combined pool of surveillance...

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Identifiers

PMID: 20174661
DOI: 10.1371/journal.pone.0009263
PMCID: PMC2822863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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