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Article

HIV-1 nucleotide mixture detection in the virco(®)TYPE HIV-1 genotyping assay: a comparison between Sanger sequencing and 454 pyrosequencing.

Journal of virological methods - 1 Jul 2011

De Wolf Hans, Van Marck Herwig, Mostmans Wendy, Thys Kim, Vandenbroucke Ina, Van Eygen Veerle, Pattery Theresa, Verhasselt Peter, Aerssens Jeroen

Abstract excerpt

HIV-1 Protease (PR) and Reverse Transcriptase (RT) genotyping is well established for the management of antiretroviral (ARV) drug therapy, as it is able to detect gene mutations encoding resistance to ARV compounds or drug classes, that are associated with reduced drug susceptibility (i.e. phenotype). A correct phenotypic interpretation from the derived PR-RT genotype (i.e. virtual phenotype), requires a well...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21549149
DOI: 10.1016/j.jviromet.2011.04.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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