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A Partially Multiplexed HIV Drug Resistance (HIVDR) Assay for Monitoring HIVDR Mutations of the Protease, Reverse-Transcriptase (PRRT), and Integrase (INT).

Microbiology spectrum - 29 Jun 2022

DeVos Joshua, McCarthy Kimberly, Sewe Victor, Akinyi Grace, Junghae Muthoni, Opollo Valarie, Nouhin Janin, Shafer Robert, Zeh Clement, Ramos Artur, Alexander Heather, Chang Joy

Abstract excerpt

As dolutegravir (DTG)-containing HIV regimens are scaled up globally, monitoring for HIV drug resistance (HIVDR) will become increasingly important. We designed a partially multiplexed HIVDR assay using Sanger sequencing technology to monitor HIVDR mutations in the protease, reverse-transcriptase (PRRT), and integrase (INT). A total of 213 clinical and analytical plasma and dried blood spot (DBS) samples were...

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Identifiers

PMID: 35510849
DOI: 10.1128/spectrum.01776-21
PMCID: PMC9241735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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