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Article

Early environmental enrichment moderates the behavioral and synaptic phenotype of MeCP2 null mice.

Biological psychiatry - 1 Apr 2010

Lonetti Giuseppina, Angelucci Andrea, Morando Laura, Boggio Elena M, Giustetto Maurizio, Pizzorusso Tommaso

Abstract excerpt

BACKGROUND: Rett syndrome (RTT) is an X-linked progressive neurodevelopmental disorder characterized by a variety of symptoms including motor abnormalities, mental retardation, anxiety, and autism. Most of RTT cases are caused by mutations of MeCP2. In mice, impaired MeCP2 function results in syn...

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Source

Identifiers

PMID: 20172507
DOI: 10.1016/j.biopsych.2009.12.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20172507-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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