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Article

Unconventional transcriptional response to environmental enrichment in a mouse model of Rett syndrome.

PloS one - 12 Jul 2010

Kerr Bredford, Silva Pamela A, Walz Katherina, Young Juan I

Abstract excerpt

BACKGROUND: Rett syndrome (RTT) is an X-linked postnatal neurodevelopmental disorder caused by mutations in the gene encoding methyl-CpG binding protein 2 (MeCP2) and one of the leading causes of mental retardation in females. RTT is characterized by psychomotor retardation, purposeless hand movements, autistic-like behavior and abnormal gait. We studied the effects of environmental enrichment (EE) on the...

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Source

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Identifiers

PMID: 20634955
DOI: 10.1371/journal.pone.0011534
PMCID: PMC2902516

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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