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Article

Environmental enrichment alters locomotor behaviour and ventricular volume in Mecp2 1lox mice.

Behavioural brain research - 3 Jan 2009

Nag Nupur, Moriuchi Jennifer M, Peitzman Cassandra G K, Ward Bonnie C, Kolodny Nancy H, Berger-Sweeney Joanne E

Abstract excerpt

Rett syndrome (RTT) is an autistic spectrum developmental disorder associated with mutations in the X-linked Mecp2 gene, and severe behavioural and neuropathological deficits. In a mouse model of RTT (Mecp2(1lox)), we examined whether environmental enrichment (EE) alters behavioural performance and regional brain volume. At weaning, Mecp2(1lox) and control mice were assigned to enriched or standard housing. From...

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Source

Identifiers

PMID: 18687363
DOI: 10.1016/j.bbr.2008.07.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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