Article
Nutritional factors in a mouse model of Rett syndrome.
Neuroscience and biobehavioral reviews - 1 Apr 2009
Nag Nupur, Ward Bonnie, Berger-Sweeney Joanne E
Abstract excerpt
Environmental factors such as nutrition and housing can influence behavioral and anatomical characteristics of several neurological disorders, including Rett syndrome (RTT). RTT is associated with mutations in the X-linked gene encoding MeCP2, a transcriptional repressor that binds methylated DNA. While direct genetic intervention in humans is impossible at this time, motor and cognitive deficits in RTT may be...
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