Article
Activity-driven mobilization of post-synaptic proteins.
The European journal of neuroscience - 3 Dec 2009
Gutiérrez R Carolina, Flynn Robyn, Hung Johanna, Kertesz Audrey C, Sullivan Andrea, Zamponi Gerald W, El-Husseini Alaa, Colicos Michael A
Abstract excerpt
Synapses established during central nervous system development can be modified through synapse elimination and formation. These processes are, in part, activity dependent and require regulated trafficking of post-synaptic components. Here, we investigate the activity-driven remodeling of cultured rat hippocampal neurons at 14 days in vitro, focusing on the post-synaptic proteins PSD-95, Shank, neuroligin (NL)1...
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