Article
Distinct domains within PSD-95 mediate synaptic incorporation, stabilization, and activity-dependent trafficking.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 14 Oct 2009
Sturgill James F, Steiner Pascal, Czervionke Brian L, Sabatini Bernardo L
Abstract excerpt
The postsynaptic density (PSD) consists of a lattice-like array of interacting proteins that organizes and stabilizes receptors, ion channels, structural, and signaling proteins necessary for synaptic function. To study the stabilization of proteins within this structure and the contribution of these proteins to the integrity of the PSD, we tagged synaptic proteins with PAGFP (photoactivatable green fluorescent...
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