Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reversible, activity-dependent targeting of profilin to neuronal nuclei.

Experimental cell research - 15 Jul 2006

Birbach Andreas, Verkuyl J Martin, Matus Andrew

Abstract excerpt

The actin cytoskeleton in pyramidal neurons plays a major role in activity-dependent processes underlying neuronal plasticity. The small actin-binding protein profilin shows NMDA receptor-dependent accumulation in dendritic spines, which is correlated with suppression of actin dynamics and long-term stabilization of synaptic morphology. Here we show that following NMDA receptor activation profilin also...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Cytoplasm
Share to Dendritic Spines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycine

Share to Magnesium

Share to N-Methylaspartate

Share to Profilins

Share to Receptors, N-Methyl-D-Aspartate

Source

Identifiers

PMID: 16716297
DOI: 10.1016/j.yexcr.2006.03.026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reversible, activity-dependent targeting of profilin to neuronal nuclei.PMID 16716297Read ↗

Profilin1 biology and its mutation, actin(g) in disease.Semantic proximity Read ↗

Amyotrophic lateral sclerosis-associated mutant profilin 1 increases dendritic arborisation and spine formation in primary hippocampal neurons.Semantic proximity Read ↗

Mechanisms and Functions of Activity-Regulated Cytoskeleton-Associated Protein in Synaptic PlasticitySemantic proximity Read ↗

Activity-driven mobilization of post-synaptic proteins.Semantic proximity Read ↗

Profilin and actin-related proteins regulate microfilament dynamics during early mammalian embryogenesisSemantic proximity Read ↗

SPIN90 dephosphorylation is required for cofilin-mediated actin depolymerization in NMDA-stimulated hippocampal neurons.Semantic proximity Read ↗

Expression of expanded polyglutamine targets profilin for degradation and alters actin dynamics.Semantic proximity Read ↗

Calcium-induced outgrowth of astrocytic peripheral processes requires actin binding by Profilin-1.Semantic proximity Read ↗

Neuronal differentiation in the rat hippocampus involves a stage-specific reorganization of subnuclear structure both in vivo and in vitro.Semantic proximity Read ↗

A nuclear actin function regulates neuronal motility by serum response factor-dependent gene transcription.Semantic proximity Read ↗

Neuron-enriched phosphatase and actin regulator 3 (Phactr3)/ nuclear scaffold-associated PP1-inhibiting protein (Scapinin) regulates dendritic morphology via its protein phosphatase 1-binding domain.Semantic proximity Read ↗

Actin-associated neurabin-protein phosphatase-1 complex regulates hippocampal plasticity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.