Article
Bioluminescence imaging of Arc expression enables detection of activity-dependent and plastic changes in the visual cortex of adult mice.
Brain structure & function - 1 Jun 2011
Izumi Hironori, Ishimoto Tetsuya, Yamamoto Hiroshi, Nishijo Hisao, Mori Hisashi
Abstract excerpt
Induction of the activity-regulated cytoskeleton-associated protein gene (Arc), one of the immediate early genes, in the brain correlates with various sensory processes, natural behaviors, and pathological conditions. Arc is also involved in synaptic plasticity during development. Thus, in vivo monitoring of Arc expression is useful for the analysis of physiological and pathological conditions in the brain....
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