Article

14-3-3 shuttles Activity-dependent neuroprotective protein to the cytoplasm to promote appropriate neuronal morphogenesis, cortical connectivity and calcium signaling

2020-05-27

Abstract excerpt

Neurite formation is the earliest stage of neuronal morphogenesis, where primitive dendrites and the primitive axon emerge from a spherical neuron and begin to elongate. Defective neuritogenesis is a contributing pathogenic mechanism behind a variety of neurodevelopmental disorders. Activity-dependent neuroprotective protein (Adnp) is essential to embryonic and postnatal brain development, and mutations in ADNP a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2914f374-a9c8-5e1c-81c5-1cc44beb95ca
DOI: 10.1101/2020.05.26.105015

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

14-3-3 shuttles Activity-dependent neuroprotective protein to the cytoplasm to promote appropriate neuronal morphogenesis, cortical connectivity and calcium signalingDOI 10.1101/2020.05.26.105015Read

Activity-dependent neuroprotective protein deficiency models synaptic and developmental phenotypes of autism-like syndrome.Semantic proximity Read

Laugier-Hunziker syndrome: an important differential diagnosis for Peutz-Jeghers syndrome: Figure 1Semantic proximity Read

GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons.Semantic proximity Read

The atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics.Semantic proximity Read

Extracellular vesicles from stem cells rescue cellular phenotypes and behavioral deficits in SHANK3-associated ASD neuronal and mouse models.Semantic proximity Read

Viral vectors with cluster of differentiation gene promoters to target specific cell types in the brainSemantic proximity Read

Nna1 mediates Purkinje cell dendritic development via lysyl oxidase propeptide and NF-κB signaling.Semantic proximity Read

ASD gene <i>Bcl11a</i> regulates subcellular RNA localization, associative circuitry, and social behaviorSemantic proximity Read

Glutathione S-transferase Pi (Gstp) Proteins Regulate Neuritogenesis in the Developing Cerebral CortexSemantic proximity Read

CNTNAP2 stabilizes interneuron dendritic arbors through CASK.Semantic proximity Read

ARHGEF6-dependent cytoskeletal regulation underlies a conserved program of forebrain interneuron developmentSemantic proximity Read

Synapse-to-nucleus communication: from developmental disorders to Alzheimer's diseaseSemantic proximity Read