Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic alterations and changes in expression of histone demethylases in prostate cancer.

The Prostate - 1 Jun 2010

Suikki Hanna E, Kujala Paula M, Tammela Teuvo L J, van Weerden Wytske M, Vessella Robert L, Visakorpi Tapio

Abstract excerpt

BACKGROUND: Histone demethylases LSD1, JHDM2A, and GASC1 have been suggested to function as androgen receptor co-activators, and to be involved in prostate cancer (PC) progression. We aim to identify genetic alterations and changes in expression of these genes in PC. METHODS: PC cell lines, xenog...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, High Pressure Liquid
Share to Histone Demethylases
Share to Jumonji Domain-Containing Histone Demethylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Prostate

Share to Prostatic Hyperplasia

Share to Prostatic Neoplasms

Share to Statistics, Nonparametric

Share to Tissue Array Analysis

Source

Identifiers

PMID: 20127736
DOI: 10.1002/pros.21123

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20127736-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic alterations and changes in expression of histone demethylases in prostate cancer.PMID 20127736Read ↗

Selective reduction of AKR1C2 in prostate cancer and its role in DHT metabolismSemantic proximity Read ↗

Deregulated expression of selected histone methylases and demethylases in prostate carcinomaSemantic proximity Read ↗

The emerging role of histone lysine demethylases in prostate cancerSemantic proximity Read ↗

IDH1R132H Promotes Malignant Transformation of Benign Prostatic Epithelium by Dysregulating MicroRNAs: Involvement of IGF1R-AKT/STAT3 Signaling Pathway.Semantic proximity Read ↗

LSD1 Inhibition Disrupts Super-Enhancer–Driven Oncogenic Transcriptional Programs in Castration-Resistant Prostate CancerSemantic proximity Read ↗

Alterations in promoter methylation status of tumor suppressor HIC1, SFRP2, and DAPK1 genes in prostate carcinomas.Semantic proximity Read ↗

NMD and microRNA expression profiling of the HPCX1 locus reveal MAGEC1 as a candidate prostate cancer predisposition gene.Semantic proximity Read ↗

DNA methyltransferase and demethylase in human prostate cancerSemantic proximity Read ↗

LSD1 activates a lethal prostate cancer gene network independently of its demethylase functionSemantic proximity Read ↗

Gene expression profile and mutational analysis of DNA mismatch repair genes in carcinoma prostate in Indian population.Semantic proximity Read ↗

Role of Genetic Variations in CDK2, CCNE1 and p27KIP1 in Prostate Cancer.Semantic proximity Read ↗

HPC2 variants and screen-detected prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.