Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA methyltransferase and demethylase in human prostate cancer

20 Feb 2002

Abstract excerpt

Recent studies have shown that cytosine-5 methylation at CpG islands in the regulatory sequence of a gene is one of the key mechanisms of inactivation. The enzymes responsible for CpG methylation are DNA methyltransferase (DNMT) 1, DNMT3a, and DNMT3b, and the enzyme responsible for demethylation is DNA demethylase (MBD2). Studies on methylation-demethylation enzymes are lacking in human prostate cancer. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Prostate Cancer Treatment and Research
Share to Urological Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11870882
DOI: 10.1002/mc.10033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA methyltransferase and demethylase in human prostate cancerPMID 11870882Read ↗

Epigenetic Changes in Prostate Cancer: Implication for Diagnosis and TreatmentSemantic proximity Read ↗

Aberrant DNA Methylation and Prostate CancerSemantic proximity Read ↗

Increased levels of DNA methyltransferases are associated with the tumorigenic capacity of prostate cancer cells.Semantic proximity Read ↗

Epigenetics in Prostate CancerSemantic proximity Read ↗

DNA methylation changes in prostate cancer: current developments and future clinical implementationSemantic proximity Read ↗

Recent advances in understanding DNA methylation of prostate cancerSemantic proximity Read ↗

Deregulated expression of selected histone methylases and demethylases in prostate carcinomaSemantic proximity Read ↗

Integrated Analysis of Genetic Abnormalities of the Histone Lysine Methyltransferases in Prostate CancerSemantic proximity Read ↗

DNA Methylation in Prostate Cancer: Clinical Implications and Potential ApplicationsSemantic proximity Read ↗

Abnormal DNA methylation, epigenetics, and prostate cancerSemantic proximity Read ↗

Epigenetic regulation of prostate cancerSemantic proximity Read ↗

Promoter Hypermethylation in Prostate CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.