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Article

HPC2 variants and screen-detected prostate cancer.

American journal of human genetics - 1 Apr 2001

Vesprini D, Nam R K, Trachtenberg J, Jewett M A, Tavtigian S V, Emami M, Ho M, Toi A, Narod S A

Abstract excerpt

Two studies have reported significant associations between susceptibility to prostate cancer and two common missense variants of the HPC2/ELAC2 gene, with estimated relative risks in the range of two- to threefold. We investigated whether these polymorphisms could be informative in the prediction of the presence of prostate cancer in men undergoing prostatic biopsy for the evaluation of an elevated serum-PSA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11254449
DOI: 10.1086/319502
PMCID: PMC1275645

Genes

ELAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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