Article
Gene expression profile and mutational analysis of DNA mismatch repair genes in carcinoma prostate in Indian population.
Omics : a journal of integrative biology - 1 May 2011
Soni Abha, Bansal Anju, Singh L C, Mishra Ashwani K, Majumdar Mainak, Regina Thoudam, Mohanty N K, Saxena Sunita
Abstract excerpt
DNA mismatch repair (MMR) plays a role in promoting genetic stability by repairing DNA replication errors, inhibiting recombination between nonidentical DNA sequences, and participating in responses to DNA damage. Although the role of MMR in prostate carcinogenesis remains unclear, MMR deficiency in Carcinoma Prostate (Pca) could prove to be clinically significant. Thus, the present study investigated the gene...
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