Article
Role of Genetic Variations in CDK2, CCNE1 and p27KIP1 in Prostate Cancer.
Cancer genomics & proteomics - 1 Jan 2000
Híveš Márk, Jurečeková Jana, Kliment Ján, Grendár Marián, Kaplán Peter, Dušenka Róbert, Evin Daniel, Vilčková Marta, Holečková Klaudia Híveš, Sivoňová Monika Kmeťová
Abstract excerpt
BACKGROUND/AIM: Our aim was to investigate possible influences of genetic variants in genes involved in the G1/S transition [cyclin-dependent kinase-2 (CDK2), cyclin E1 (CCNE1) and cyclin-dependent kinase inhibitor 1B (p27KIP1)] on the expression/activity of their corresponding proteins and to assess the functional impact of these variants on the risk of prostate cancer. MATERIALS AND METHODS: We genotyped 530...
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