Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The emerging role of histone lysine demethylases in prostate cancer

1 Jan 2012

Abstract excerpt

Early prostate cancer (PCa) is generally treatable and associated with good prognosis. After a variable time, PCa evolves into a highly metastatic and treatment-refractory disease: castration-resistant PCa (CRPC). Currently, few prognostic factors are available to predict the emergence of CRPC, and no curative option is available. Epigenetic gene regulation has been shown to trigger PCa metastasis and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22867098
DOI: 10.1186/1476-4598-11-52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The emerging role of histone lysine demethylases in prostate cancerPMID 22867098Read ↗

Bioinformatic determination of the expression and clinical value of the histone lysine demethylase family in prostate cancerSemantic proximity Read ↗

Therapeutic targeting of histone lysine demethylase KDM4B blocks the growth of castration-resistant prostate cancerSemantic proximity Read ↗

Deregulated expression of selected histone methylases and demethylases in prostate carcinomaSemantic proximity Read ↗

Epigenetic Changes in Prostate Cancer: Implication for Diagnosis and TreatmentSemantic proximity Read ↗

Therapeutic Targeting of Histone Lysine Demethylase KDM4B Blocks the Growth of Castration-Resistant Prostate CancerSemantic proximity Read ↗

Histone Demethylase KDM5C Drives Prostate Cancer Progression by Promoting EMTSemantic proximity Read ↗

Epigenetic Regulation in Prostate Cancer ProgressionSemantic proximity Read ↗

Epigenetics in prostate cancer: clinical implicationsSemantic proximity Read ↗

DNA methylation alterations in prostate cancer: from diagnosis to treatmentSemantic proximity Read ↗

Epigenetic insights into prostate cancer: exploring histone modifications and their therapeutic implicationsSemantic proximity Read ↗

Epigenetics in Prostate CancerSemantic proximity Read ↗

Integrative analyses of DNA methylase expression and related immune landscape in Prostate CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.