Article
Cognitive and social functions and growth factors in a mouse model of Rett syndrome.
Physiology & behavior - 1 Jun 2010
Schaevitz Laura R, Moriuchi Jennifer M, Nag Nupur, Mellot Tiffany J, Berger-Sweeney Joanne
Abstract excerpt
Rett syndrome (RTT) is an autism-spectrum disorder caused by mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (MeCP2). Abnormalities in social behavior, stereotyped movements, and restricted interests are common features in both RTT and classic autism. While mouse models of both RTT and autism exist, social behaviors have not been explored extensively in mouse models of RTT. Here, we report...
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