Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mouse models of Rett syndrome: from behavioural phenotyping to preclinical evaluation of new therapeutic approaches.

Behavioural pharmacology - 1 Sept 2008

Ricceri Laura, De Filippis Bianca, Laviola Giovanni

Abstract excerpt

Rett syndrome (RTT) is a neurodevelopmental disorder, primarily affecting girls. RTT causes severe cognitive, social, motor and physiological impairments and no cure currently exists. The discovery of a monogenic origin for RTT and the subsequent generation of RTT mouse models provided a major br...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Drug Evaluation, Preclinical
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Therapy

Share to Methyl-CpG-Binding Protein 2

Share to Mice, Transgenic

Share to Psychotropic Drugs

Share to Rett Syndrome

Source

Identifiers

PMID: 18690105
DOI: 10.1097/FBP.0b013e32830c3645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18690105-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mouse models of Rett syndrome: from behavioural phenotyping to preclinical evaluation of new therapeutic approaches.PMID 18690105Read ↗

Rett syndrome treatment in mouse models: searching for effective targets and strategies.Semantic proximity Read ↗

Mice with an isoform-ablating Mecp2 exon 1 mutation recapitulate the neurologic deficits of Rett syndrome.Semantic proximity Read ↗

Mirtazapine treatment in a young female mouse model of Rett syndrome identifies time windows for the rescue of early phenotypes.Semantic proximity Read ↗

MeCP2 R168X male and female mutant mice exhibit Rett-like behavioral deficits.Semantic proximity Read ↗

Rett syndrome and MeCP2.Semantic proximity Read ↗

Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.Semantic proximity Read ↗

Rett syndrome: a prototypical neurodevelopmental disorder.Semantic proximity Read ↗

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome.Semantic proximity Read ↗

The story of Rett syndrome: from clinic to neurobiology.Semantic proximity Read ↗

Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering.Semantic proximity Read ↗

Mirtazapine treatment in a young female mouse model of Rett syndrome identifies time windows for the rescue of early phenotypes during developmentSemantic proximity Read ↗

Translational research: Rett syndrome and tuberous sclerosis complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.