Article
Behavioral phenotypes of genetic mouse models of autism.
Genes, brain, and behavior - 1 Jan 2016
Kazdoba T M, Leach P T, Crawley J N
Abstract excerpt
More than a hundred de novo single gene mutations and copy-number variants have been implicated in autism, each occurring in a small subset of cases. Mutant mouse models with syntenic mutations offer research tools to gain an understanding of the role of each gene in modulating biological and behavioral phenotypes relevant to autism. Knockout, knockin and transgenic mice incorporating risk gene mutations detected...
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