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Article

DNA repair gene XRCC1 polymorphisms and outcome of renal cell carcinoma in Caucasian patients.

Anticancer research - 1 Dec 2009

Bachmann Hagen S, Rübben Herbert, Schmid Kurt W, Siffert Winfried, Riemann Kathrin

Abstract excerpt

BACKGROUND: The human X-ray repair cross-complementing group 1 (XRCC1) enzyme plays an important role in response to DNA damage. Two common polymorphisms in XRCC1, Arg194Trp and Arg399Gln, have been repeatedly associated with risk for and outcome of numerous types of cancer treated with radio- and chemotherapy. Recently, a Japanese study suggested these polymorphisms both as risk factors and outcome predictors in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20044627

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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