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Article

Polymorphisms of DNA repair genes are associated with renal cell carcinoma.

Biochemical and biophysical research communications - 21 Apr 2006

Hirata Hiroshi, Hinoda Yuji, Matsuyama Hideyasu, Tanaka Yuichiro, Okayama Naoko, Suehiro Yutaka, Zhao Hong, Urakami Shinji, Kawamoto Ken, Kawakami Toshifumi, Igawa Mikio, Naito Katsusuke, Dahiya Rajvir

Abstract excerpt

DNA repair gene alterations have been shown to cause a reduction in DNA repair capacity and may influence an individual's susceptibility to carcinogenesis. Single nucleotide polymorphisms (SNPs) of DNA repair genes have been shown to cause a reduction in repair activity. We hypothesized that SNPs of DNA repair genes may be a risk factor for renal cell carcinoma (RCC). To test this hypothesis, DNA samples from 112...

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Share to Carcinoma, Renal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16510122
DOI: 10.1016/j.bbrc.2006.02.030

Genes

XRCC1
ERCC1
XPC
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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