Article
The association of DNA repair gene polymorphisms with the development and progression of renal cell carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Nov 2007
Sakano S, Hinoda Y, Okayama N, Kawai Y, Korenaga Y, Eguchi S, Nagao K, Ohmi C, Naito K
Abstract excerpt
BACKGROUND: DNA repair enzymes repair some of the DNA damage associated with risk factors for renal cell carcinoma (RCC), including smoking. DNA repair gene polymorphisms modulate the repair capacity and might influence individual risk and progression of RCC. We examined associations between functional polymorphisms and risk, clinicopathologic characteristics and survival of RCC. PATIENTS AND METHODS: The study...
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