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Article

XRCC1 Arg399Gln polymorphism and bladder cancer risk: updated meta-analyses based on 5767 cases and 6919 controls.

Experimental biology and medicine (Maywood, N.J.) - 1 Jan 2013

Zhuo Wenlei, Zhang Liang, Cai Lei, Zhu Bo, Chen Zhengtang

Abstract excerpt

Previous reports implicate XRCC1 Arg399Gln polymorphism as a possible risk factor for several cancers. Published meta-analyses have been conducted on the association of XRCC1 Arg399Gln polymorphism with susceptibility to bladder cancer, and have generated conflicting results. The present study aimed to derive a more precise estimation of the relationship. Updated meta-analyses assessing the association of XRCC1...

Topics

Adult
Aged
Aged, 80 and over
DNA-Binding Proteins
Ethnicity
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Male
Middle Aged
Mutation, Missense

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Smoking

Urinary Bladder Neoplasms

X-ray Repair Cross Complementing Protein 1

Young Adult

Source

Identifiers

PMID: 23479765
DOI: 10.1258/ebm.2012.012209

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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XRCC1 Arg399Gln polymorphism and bladder cancer risk: updated meta-analyses based on 5767 cases and 6919 controls.PMID 23479765Read ↗

Meta-analysis demonstrates no association between XRCC1 Arg399Gln polymorphism and bladder cancer risk.Semantic proximity Read ↗

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XRCC1 genetic polymorphisms and bladder cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

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Meta-analysis of the association between the XRCC1 gene R399Q polymorphism and colorectal cancer: an update.Semantic proximity Read ↗

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