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Article

Predictive value of XRCC1 gene polymorphisms on platinum-based chemotherapy in advanced non-small cell lung cancer patients: a systematic review and meta-analysis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2012

Wu Junjie, Liu Jie, Zhou Yuhao, Ying Jun, Zou Houdong, Guo Shicheng, Wang Lei, Zhao Naiqing, Hu Jianjun, Lu Daru, Jin Li, Li Qiang, Wang Jiu-Cun

Abstract excerpt

PURPOSE: Published data have shown conflicting results about the relationship between X-ray repair cross-complementing group 1 (XRCC1) gene polymorphisms (Arg399Gln and Arg194Trp) and clinical outcome of platinum-based chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). A meta-analysis is needed to provide a systematic review of the published findings. EXPERIMENTAL DESIGN: We conducted a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22705987
DOI: 10.1158/1078-0432.CCR-11-1531

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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