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Article

No association between XRCC1 polymorphisms and survival in non-small-cell lung cancer patients treated with platinum-based chemotherapy.

Cancer biology & therapy - 1 Nov 2010

Yuan Peng, Liu Li, Wu Chen, Zhong Rong, Yu Dianke, Wu Jing, Xu Yihua, Nie Shaofa, Miao Xiaoping, Sun Yan, Xu Binghe, Lin Dongxin

Abstract excerpt

PURPOSE: genetic polymorphisms in DNA repair genes are thought to represent important determinants of platinum drug efficacy. The current study investigated whether single nucleotide polymorphisms (SNPs) in the X-ray repair cross complementing protein 1 (XRCC1) gene are associated with survival in non-small-cell lung cancer (NSCLC) patients treated with platinum-based chemotherapy. EXPERIMENTAL DESIGN: a total of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20814250
DOI: 10.4161/cbt.10.9.13238

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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